human genome project - what is it? and what did we learn from it?
The work of the Human Genome Project has allowed researchers to begin to understand the blueprint for building a person. As researchers learn more about the functions of genes and proteins, this knowledge will have a major impact in the fields of medicine, biotechnology, and the life sciences.
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This "My Genome Sequence" video will help you to discover what your genome is and how the technology behind whole genome sequencing works. The short animation, aimed at young people, explains what genome sequencing is and what happens when patients have their genom. In 1990, The Human Genome Project proposed to sequence the entire human genome over 15 years with $3 billion of public funds. Then, seven years before its scheduled completion, a private company called Celera announced that they could accomplish the same goal in just three years at a fraction of the cost. Tien Nguyen details the history of this race to sequence the human genome. Prominent scientists involved in the Human Genome Project reflect on the lessons learned. 
Intrigued? learn more about bug-eyed, toothless, tiny cat called Lil Bub (the internet-breaking Queen of Cute) and sequencing her Magical genome here..
Humans are 99.9% genetically identical and yet we are all so different. How can this be? This video, taken from a lesson in Harvard Medical School Genetics course. |
I. what is "my genome sequence"?
II. THE RACE TO SEQUENCE
III. lessons learned
IV. INTRO TO HUMAN GENOME
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Next Gen Sequencing includes the so called ´Sequencing by Synthesis` and with that procedure it is possible to sequence a human genome in a single day. P.C.R (Polymerase Chain Reaction) mentioned in the video occurs in three steps :: denaturing, annealing and extension. Intrigued? You can learn more about P.C.R and How to perform P.C.R at the Lab Bench here.. |
V : intro to next generation/deep sequencing
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