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Living cells are highly sophisticated computational machines, constantly processing information to survive, grow and reproduce.
The software allows the desired behaviour of a molecular device to be programmed, simulated, analysed and then automatically compiled to DNA code, which could then be inserted into cells to reprogram their behaviour. Learn more about Biological computation research at Microsoft here ..
PROGRAM CELLS TO SELF DESTRUCT
Biomedical engineer Jordan Green talks about a goal of his research: making nano-particles that could program cancer cells to self-destruct. More about Dr. Green Group Biomaterials and Drug Delivery Laboratory in the Biomedical Engineering Department at the Johns Hopkins University School of Medicine here.. |
I of V: Hacking bacteria to fight disease
II of V: programming cells at microsoft research
III of V: the software
IV of V : program cancer cells to self destruct
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gro :: A programming
Rise of Nations meets gro! In this simulaton, strains of E. coli form nations, each with one leader to control its population. As the cells grow and divide, they get weaker/hungrier. The weaker a cell is, the darker its fluorescence. For the cells to eat and regain their strength, some must lyse (kill themselves) to release food. It is up to the leader cell of each nation to determine how many cells will lyse and when. When the two opposing nations meet, they will fight to kill each other. Only the strongest and largest nation will survive
Learn more about gro here BUILD CELL SIGNALING NETWORK
Dr. Lim explains that many signaling proteins are built from simple modules arranged in different ways |
V of V: Rise of E. coli Nations - Gro Simulation - University of Washington
IV of IV : Building cell signaling network
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